Effects of electrostatic interactions on ligand dissociation kinetics
نویسندگان
چکیده
منابع مشابه
Effects of electrostatic interactions on ligand dissociation kinetics.
We study unbinding of multivalent cationic ligands from oppositely charged polymeric binding sites sparsely grafted on a flat neutral substrate. Our molecular dynamics simulations are suggested by single-molecule studies of protein-DNA interactions. We consider univalent salt concentrations spanning roughly a 1000-fold range, together with various concentrations of excess ligands in solution. T...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2018
ISSN: 2470-0045,2470-0053
DOI: 10.1103/physreve.97.022405